Gene Linked To Common Ailment In Labrador Retrievers Identified

Gene Linked To Common Ailment In Labrador Retrievers Identified
Researchers at the University of Minnesota College of Veterinary Medicine have identified a gene in Labrador retriever dogs highly associated with the syndrome of exercise-induced collapse (EIC). After intense hunting or retrieving exercise, activities these dogs are trained to perform, affected Labradors start to lose control of their hind limbs. In most cases, their legs get wobbly and the limbs give out, and in rare cases the dogs may die. Labradors are the most common dog breed in the world and an estimated 3-5 percent of Labradors have this condition.
The research is published in the journal Nature Genetics.
The research team identified a mutant form of the dynamin 1 gene as highly associated with EIC. The dynamin 1 protein normally functions to maintain proper chemical communication between adjacent nerves, also known as synaptic transmission. However, the mutated form of the dynamin protein appears to have diminished function, interrupting synaptic transmission during intense exercise, and causing the muscle-controlling nerves to not fire when directed to do so.
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Some of you may not be aware but dog breeds like labrador retriever puppies can develop what is called canine acne. Canine acne usually breaks out on their chin, lips, and muzzle. It can also be associated with scabs and blackheads on their lips, chin and muzzle. While not usually harmful it can become infected which leads to many other problems.



